A brief review of the basics of immunology: the innate and adaptive response
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Updated: Jun 13, 2026

Quantification of the Respiratory Burst Response as an Indicator of Innate Immune Health in Zebrafish
Published on: September 12, 2013
1Department of Comparative Medicine, College of Veterinary Medicine, University of Tennessee, 2407 River Drive, Knoxville, TN 37996-4543, USA. mkenned2@utk.edu
Abstract:
The role of the immune system is simple yet challenging: to eliminate pathogenic agents. The immune system contains nonspecific and specific components; that is, some constituents act without precise recognition of the target, others have exquisite specificity. Regulation of the immune response and maintenance of tolerance to self are critical to the health of the animal. To properly evaluate or control immune function, knowledge of the basic components of the normal immune system is essential. This review covers the current knowledge of individual components of the immune system and how they interact to protect the host from infectious disease agents.
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