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Functional electrical stimulation to lower limb muscles after botox in children with cerebral palsy
Anja Seifart1, Marianne Unger, Marlett Burger
1Department of Physiotherapy, Faculty of Health Sciences, University of Stellenbosch, Cape Town, South Africa. anjaseifart@webmail.co.za
Insights
Functional electrical stimulation (FES) after botulinum toxin injection in children with cerebral palsy improved plantar flexor strength. The optimal timing for FES initiation was around 32 days post-injection for best results.
Area of Science:
- Pediatric Rehabilitation
- Neuromuscular Electrical Stimulation
Background:
- Cerebral palsy (CP) often leads to gait impairments.
- Botulinum toxin injections are used to manage spasticity in CP.
- Functional electrical stimulation (FES) is a potential adjunct therapy.
Purpose of the Study:
- To evaluate the impact of lower limb FES post-botulinum toxin injection in children with CP.
- To assess effects on walking speed and muscle strength (plantar flexors and dorsiflexors).
- To determine the optimal timing for initiating FES after botulinum toxin treatment.
Main Methods:
- A single-subject design was employed with five pediatric participants with CP.
- Subjects received a botulinum toxin injection into the calf muscle.
- A 4-week home-based FES program was implemented, with adherence varying among participants.
Main Results:
- Functional electrical stimulation (FES) significantly increased isometric plantar flexor muscle strength.
- No significant changes were observed in self-selected walking speeds.
- Isometric dorsiflexor strength also did not show improvement with FES intervention.
- An interval of approximately 32 days between botulinum toxin injection and FES initiation appeared most effective.
Conclusions:
- FES following botulinum toxin injection shows promise in enhancing specific gait-related muscle strength in children with CP.
- Current findings suggest FES may be beneficial for certain gait variables, but not universally for all measures like walking speed.
- Further research is warranted to confirm these preliminary findings and optimize therapeutic protocols.
Purpose:
This study examined the effect of lower limb functional electrical stimulation (FES) after botulinum toxin injection in children with cerebral palsy on self-selected walking speed, plantar flexor and dorsiflexor muscle strength, and an optimal time frame for initiating FES after the injection.
Methods:
Five subjects participated in a single-subject design. All subjects received a single botulinum toxin injection into the calf muscle, followed by a 4-week FES home program. Three subjects followed the protocol as prescribed; 2 subjects received no FES.
Results:
FES after botulinum toxin increased isometric plantar flexor muscle strength, but did not produce changes in self-selected walking speeds or isometric dorsiflexor strength. A 32-day interval between botulinum toxin and the start of FES was most effective.
Conclusions And Recommendations For Clinical Practice:
FES after botulinum toxin seems to be effective in improving some gait variables, although further research is needed for substantiation.

