Related Experiment Video
Updated: Oct 23, 2026

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
Published on: March 30, 2018
Mediastinal lymphoma
1Department of Pathology, Mayo Clinic, Rochester, MN 55905.
Abstract:
Malignant lymphoma may involve the mediastinum as a component of disseminated disease or as a primary lesion. The most common types of primary mediastinal lymphomas (ML) are Hodgkin's disease (HD, usually of the nodular sclerosis type), large cell lymphoma (often associated with sclerosis), and lymphoblastic lymphoma (frequently seen in conjunction with acute lymphoblastic leukemia). The characteristic clinical, morphologic, and immunophenotypic features of these three neoplasms are reviewed. ML must be distinguished from Castleman's disease, an enigmatic lymphoid proliferation that frequently involves the mediastinum.
Related Concept Videos
Secondary Lymphoid Organs
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
Mitral Stenosis I: Introduction
Mitral Stenosis II: Clinical features and Diagnostic Tests

