[CLinico-morphologic correlations in Flexner's and Sonne dysentery]

The clinical and morphological data were studied and compared in 84 patients with Flexner's dysentery and 40 with Sonne dysentery. It is established that more pronounced and lingering colitic syndrome typical of Flexner's dysentery is related to more lasting persistence of causative agents in the superficial epithelium and in the m. mucosae of the rectum. Unlike Sonne dysentery, insufficiency of the local defence mechanisms was discovered in patients with Flexner's dysentery, namely inhibition of mucus secretion, low level of elimination of microorganisms with desquamated colonocytes at the disease onset, pathological changes of interepithelial lymphocytes, ineffective phagocytosis of bacteria by macrophages of the m. mucosae during convalescence.