[Clinico-morphological comparisons in different types of dysentery]

Clinical evidence and morphological picture of rectal biopsy specimens were analysed for 125 dysentery patients. As compared to a light course, moderately severe and severe dysentery presented enhanced microbial adherence and an elevated level of large lymphocytes in the external epithelium of the rectum, deeper penetration of Shigella into crypts. On day 9-15 of the disease in attenuation of the clinical symptoms in severe and moderately dysentery morphological shifts persisted whereas the light run was associated with a marked decline of microbial invasion and cellular infiltration of the epithelium. In the protracted condition elimination of the microbes with desquamative colonocytes appeared inhibited permitting prognosis of the protraction as early as day 2-4 of the disease.