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Isolation and Functional Characterization of Human Ventricular Cardiomyocytes from Fresh Surgical Samples
Published on: April 21, 2014
[Secondary repolarization changes in patients with left ventricular hypertrophy]
Aim:
To estimate the detection rate of tension syndrome and nonspecific repolarization changes in patients with arterial hypertension (AH).
Subjects And Methods:
The electrocardiograms of 234 patients with AH (104 males and 130 females) were analyzed, by taking into account the magnitude of blood pressure (BP) elevation, the degree of an overall cardiovascular risk, the grade of hypertensive disease (HD), the presence of coronary heart disease (CHD), as well as echocardiographic and electrocardiographic voltage criteria for left ventricular hypertrophy (LVH).
Results:
The classical tension syndrome and nonspecific repolarization changes were observed in 7 and 26% of cases, respectively; no significant differences were found in their detection rates between the males and females. The frequency of repolarization changes were associated with the presence of CHD in the women and with the magnitude of BP elevation, the degree of a cardiovascular risk, the grade of HD, and the presence of both echocardiographic and electrocardiographic signs of LVH.
Conclusion:
Ventricular repolarization changes in patients with AH are a sign of severe cardiac lesion and determine the need for meticulous attention.
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