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Related Experiment Video

Updated: Jun 12, 2026

Isolation and Functional Characterization of Human Ventricular Cardiomyocytes from Fresh Surgical Samples

Isolation and Functional Characterization of Human Ventricular Cardiomyocytes from Fresh Surgical Samples

Published on: April 21, 2014

[Secondary repolarization changes in patients with left ventricular hypertrophy].

E V Blinova, G V Riabykina, T A Sakhnova

Terapevticheskii Arkhiv

|May 21, 2010

Summary

Nonspecific repolarization changes, a sign of severe cardiac issues in arterial hypertension (AH) patients, were detected in 26% of cases. These changes correlate with cardiovascular risk factors and left ventricular hypertrophy.

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Last Updated: Jun 12, 2026

Isolation and Functional Characterization of Human Ventricular Cardiomyocytes from Fresh Surgical Samples

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Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

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Published on: December 11, 2017

Area of Science:

Cardiology
Internal Medicine

Background:

Arterial hypertension (AH) is a significant risk factor for cardiovascular disease.
Electrocardiographic (ECG) findings can indicate cardiac strain and damage in hypertensive patients.

Purpose of the Study:

To determine the prevalence of tension-type syndrome and nonspecific repolarization changes in patients with arterial hypertension.
To explore associations between these ECG findings and clinical parameters.

Main Methods:

Analysis of ECGs from 234 patients with arterial hypertension.
Consideration of blood pressure elevation, cardiovascular risk, hypertensive disease grade, coronary heart disease (CHD), and left ventricular hypertrophy (LVH) criteria.

Main Results:

Tension-type syndrome detected in 7% and nonspecific repolarization changes in 26% of patients.
Repolarization changes were linked to CHD in women, and to blood pressure, cardiovascular risk, hypertensive disease, and LVH in all patients.

Conclusions:

Ventricular repolarization changes in AH patients signify significant cardiac damage.
These findings necessitate careful clinical evaluation and management.