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Published on: May 21, 2013
[Cell sources for engineered temporomandibular joint disc tissue: present and future]
1School of Stomatology, Lanzhou University, Lanzhou 730000, China.
Summary
This review explores cell sources for temporomandibular joint (TMJ) disc tissue engineering. It details six cell types, assessing their potential for regenerating TMJ disc tissue.
Area of Science:
- Biomaterials Science
- Regenerative Medicine
- Orthopedics
Context:
- Temporomandibular joint (TMJ) disc tissue engineering is an emerging field.
- Identifying optimal cell sources is critical for successful TMJ disc regeneration.
- Current research faces challenges due to the early stage of TMJ disc tissue engineering.
Purpose:
- To review and assess potential cell sources for temporomandibular joint (TMJ) disc tissue engineering.
- To provide a reference for researchers investigating TMJ disc regeneration strategies.
- To describe the suitability of six distinct cell types for TMJ disc tissue engineering.
Summary:
- This review introduces six cell types: TMJ disc native cells, chondrocytes, dermal fibroblasts, bone marrow-derived mesenchymal stem cells, adipose-derived stem cells, and embryonic stem cells.
- The potential applications of these cells in TMJ disc tissue engineering are discussed.
- The paper evaluates the feasibility of using these diverse cell populations for regenerating TMJ disc tissue.
Impact:
- This work aids researchers in selecting appropriate cell sources for TMJ disc tissue engineering.
- It provides foundational knowledge for advancing TMJ disc regeneration therapies.
- Facilitates the development of novel treatments for temporomandibular joint disorders.
