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Mandibular osteomyelitis and fracture in a patient with pyknodysostosis
Riedel Frota1, Rafael Avelar Linard, Emanuel Dias de Oliveira e Silva
1Department of Oral and Maxillofacial Surgery, Dentistry College Pernambuco, Pernambuco State University, Recife, Brazil. riedelfrota@uol.com.br
Abstract:
Pyknodysostosis is a rare, recessive, hereditary, autosomal disease belonging to the group of bone dysplasias. Complications such as osteomyelitis and fractures of the mandible are not uncommon and appear in the most varied forms. We report a case of chronic osteomyelitis with subsequent mandible fracture, which was successfully treated with the use of a reconstruction plate and antibiotic therapy. This article outlines the clinical and radiographic characteristics of this condition based on the clinical case described and proposes an approach regarding the best form of treatment. Considering the risks of fracture subsequent to removal of the graft from long bones as well as the presence of chronic infection, difficult-to-defeat infection, and bone contact on the compression band, the best choice is a more conservative treatment.
Insights
Pyknodysostosis, a rare bone dysplasia, can lead to chronic osteomyelitis and mandible fractures. Successful treatment involved reconstruction plates and antibiotics, highlighting conservative approaches for this rare genetic disorder.
Area of Science:
- Genetics
- Orthopedics
- Pathology
Background:
- Pyknodysostosis is a rare autosomal recessive hereditary bone dysplasia.
- Mandibular fractures and osteomyelitis are known complications of pyknodysostosis.
Observation:
- A case of chronic osteomyelitis with a subsequent mandible fracture in a pyknodysostosis patient is presented.
- The patient's condition involved difficult-to-treat chronic infection and bone contact issues.
Findings:
- Successful treatment was achieved using a reconstruction plate and antibiotic therapy.
- Conservative management is proposed as the preferred approach due to risks associated with bone grafting.
Implications:
- This case highlights the importance of considering conservative treatment options for complex mandibular complications in pyknodysostosis.
- Early diagnosis and tailored treatment strategies are crucial for managing patients with this rare genetic condition.
