Related Experiment Video
Updated: Jun 12, 2026

Iridium(III) Luminescent Probe for Detection of the Malarial Protein Biomarker Histidine Rich Protein-II
Published on: July 7, 2015
A highly sensitive and selective detection of Hg(II) in 100% aqueous solution with fluorescent labeled dimerized Cys
Bishnu Prasad Joshi1, Chuda Raj Lohani, Keun-Hyeung Lee
1Bioorganic Chemistry Lab, Department of Chemistry, Inha University, 253-Yunghyun-dong, Nam-gu, Incheon 402-751, South Korea.
Abstract:
A simple design of a ratiometric fluorescent sensor for detecting Hg(II) ion in 100% aqueous solution was demonstrated, based on the structure of dimerized Cys residues with two dansyl fluorophores. The sensor highly sensitively and selectively detected mercury ion (K(d) = 41 nM) in 100% aqueous solution via a turn-on and ratiometric response. The sensor showed no interferences of other metal ions and satisfied for monitoring the maximum allowable level (2 ppb) of mercury ion in drinking water demanded by EPA via a turn-on response.

