Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features01:24

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Virtual communication is commonly used in Finnish interstitial lung disease multidisciplinary meetings.

European clinical respiratory journal·2023
Same author

National data on prevalence of idiopathic pulmonary fibrosis and antifibrotic drug use in Finnish specialised care.

BMJ open respiratory research·2022
Same author

The fate of aspergilloma patients after surgical treatment-experience from 22 cases.

Journal of thoracic disease·2019
Same author

Demographics and survival of patients with idiopathic pulmonary fibrosis in the FinnishIPF registry.

ERJ open research·2019
Same author

Analysis of the Histologic Features Associated With Interobserver Variation in Idiopathic Pulmonary Fibrosis.

The American journal of surgical pathology·2018
Same author

Are physicians in primary health care able to recognize pulmonary fibrosis?

European clinical respiratory journal·2017

Related Experiment Video

Updated: Jun 12, 2026

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis
09:52

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis

Published on: March 9, 2018

[Allergic bronchopulmonary aspergillosis].

Ulla Hodgson1

  • 1HYKS:n keuhkosairauksien klinikka, PL 340, 00029 HUS.

Duodecim; Laaketieteellinen Aikakauskirja
|May 22, 2010
PubMed
Summary

Allergic bronchopulmonary aspergillosis (ABPA) affects 2500-5000 in Finland. Early detection and treatment with corticosteroids and antifungals improve lung health and prognosis.

Area of Science:

  • Pulmonology
  • Infectious Diseases
  • Genetics

Context:

  • Allergic bronchopulmonary aspergillosis (ABPA) is a lung condition affecting individuals with asthma or cystic fibrosis.
  • Estimated prevalence in Finland ranges from 2500 to 5000 patients.
  • Exposure to Aspergillus fungus can trigger airway inflammation in susceptible individuals.

Purpose:

  • To describe the epidemiology, pathogenesis, treatment, and prognosis of ABPA.
  • To highlight the role of genetic factors and bronchial epithelial cells in ABPA development.
  • To emphasize the importance of early diagnosis and intervention for favorable outcomes.

Summary:

  • ABPA involves airway inflammation and potential lung damage due to Aspergillus exposure, particularly in asthma and cystic fibrosis patients.

More Related Videos

Confocal Laser Scanning Microscopy-Based Quantitative Analysis of Aspergillus fumigatus Conidia Distribution in Whole-Mount Optically Cleared Mouse Lung
15:01

Confocal Laser Scanning Microscopy-Based Quantitative Analysis of Aspergillus fumigatus Conidia Distribution in Whole-Mount Optically Cleared Mouse Lung

Published on: September 18, 2021

Related Experiment Videos

Last Updated: Jun 12, 2026

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis
09:52

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis

Published on: March 9, 2018

Confocal Laser Scanning Microscopy-Based Quantitative Analysis of Aspergillus fumigatus Conidia Distribution in Whole-Mount Optically Cleared Mouse Lung
15:01

Confocal Laser Scanning Microscopy-Based Quantitative Analysis of Aspergillus fumigatus Conidia Distribution in Whole-Mount Optically Cleared Mouse Lung

Published on: September 18, 2021

  • Current treatments focus on inflammation control with oral corticosteroids and Aspergillus eradication with antifungals like itraconazole.
  • Prompt diagnosis and treatment are crucial for a good long-term prognosis.

    • Impact:

    • Provides an overview of ABPA for clinicians and researchers.
    • Informs public health strategies for managing this fungal-related respiratory disease.
    • Underscores the need for continued research into genetic predispositions and novel therapeutic approaches.