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Myeloproliferative disorders and the hyperviscosity syndrome
Bruce D Adams1, Russell Baker, J Abraham Lopez
1Department of Clinical Investigation, William Beaumont Army Medical Center, 5005 North Piedras Street, El Paso, TX 79920-5001, USA. bruce.adams@amedd.army.mil
Hematology/Oncology Clinics of North America
|May 22, 2010
Summary
Myeloproliferative disorders can cause serum hyperviscosity syndrome, a medical emergency. Prompt recognition and management, including plasma exchange, are crucial for patient outcomes.
Area of Science:
- Hematology
- Emergency Medicine
Background:
- Myeloproliferative disorders can lead to serum hyperviscosity syndrome.
- Hyperviscosity results from abnormal blood cell or protein levels.
Purpose of the Study:
- To highlight the emergent nature of myeloproliferative disorders and hyperviscosity syndrome.
- To inform emergency medicine providers about recognition and management.
Main Methods:
- Review of clinical presentations and management strategies for hyperviscosity syndrome.
- Emphasis on supportive care and early definitive treatments like apheresis.
Main Results:
- Serum hyperviscosity syndrome presents with bleeding, visual, and neurologic symptoms.
- Rapid intervention is necessary to prevent severe complications.
Conclusions:
- Emergency physicians must be prepared to manage hyperviscosity syndrome.
- Early hematology consultation and treatments like plasma exchange are vital.
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