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Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain
09:35

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Published on: May 10, 2017

[Postherpetic neuralgia].

F Mahn1, R Baron

  • 1Sektion für Neurologische Schmerzforschung und -therapie, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Kiel, Germany.

Klinische Monatsblatter Fur Augenheilkunde
|May 22, 2010
PubMed
Summary
This summary is machine-generated.

Postherpetic neuralgia (PHN) treatment has advanced, requiring early intervention to prevent chronic pain. Effective therapies include antidepressants, antiepileptics like gabapentin and pregabalin, and topical agents.

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Area of Science:

  • Neurology and pain management research.
  • Understanding neuropathic pain syndromes.

Context:

  • Postherpetic neuralgia (PHN) is a neuropathic pain syndrome following herpes zoster.
  • Affects trigeminal nerve in 20% of cases; characterized by persistent pain.
  • Incidence increases with age, with 50-75% of patients in their 70s developing PHN.

Purpose:

  • To review current findings and therapeutic options for PHN.
  • To highlight the importance of early pain management to prevent chronicity.
  • To discuss the pathophysiology and treatment strategies for PHN.

Summary:

  • PHN presents with distinct pain types: spontaneous burning, sharp lancinating pain, and mechanical allodynia.
  • Pathophysiology involves peripheral/central sensitization and spontaneous activity of damaged nociceptive fibers.
  • Effective treatments include antidepressants, antiepileptics (gabapentin, pregabalin), opioids (oxycodone, tramadol), and topical agents (capsaicin, lidocaine).

Impact:

  • Advances in understanding PHN pathophysiology have improved treatment strategies.
  • Early and adequate pain therapy is crucial for preventing chronic PHN.
  • Evidence-based pharmacological interventions offer effective management for PHN patients.