Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Characteristic histopathology of phenprocoumon-induced liver injury: correlation with clinical presentation and outcome.

Virchows Archiv : an international journal of pathology·2026
Same author

[Klatskin tumors-differentiated surgical treatment].

Chirurgie (Heidelberg, Germany)·2026
Same author

SD-OCT-histopathologic correlation in Schnabel's cavernous optic nerve atrophy.

Eye (London, England)·2025
Same author

Semi-automated quantification of vitreal hyperreflective foci in SD-OCT and their relevance in patients with peripheral retinal breaks.

BMC ophthalmology·2023
Same author

[COVID-19-associated acute macular neuroretinopathy].

Die Ophthalmologie·2022
Same author

[Recommendations of the DGAI, BDA, DOG, BDOC and BVA on anesthesiological care in ophthalmic surgery : In the version from 3 March 2021].

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·2021
Same journal

Corneal Neurotisation in Neurotrophic Keratopathy: A Retrospective Analysis of Functional Outcomes and Clinical Courses.

Klinische Monatsblatter fur Augenheilkunde·2026
Same journal

Evaluating the Long-term Success and Safety of Canaloplasty in Glaucoma Patients.

Klinische Monatsblatter fur Augenheilkunde·2026
Same journal

Imbalanced Trace Elements as Risk Factors in the Pathogenesis of Glaucoma.

Klinische Monatsblatter fur Augenheilkunde·2026
Same journal

Malnutrition as a Risk Factor for Cerebral and Glaucomatous Neurodegeneration - Mechanisms and Therapeutic Strategies.

Klinische Monatsblatter fur Augenheilkunde·2026
Same journal

Impact of Wearing a Face Mask on the Reliability of Standard Automated Perimetry in Glaucoma Patients and Suspects: a Retrospective Longitudinal Study.

Klinische Monatsblatter fur Augenheilkunde·2026
Same journal

[Siderotic Cataract Eight Months After Intralenticular Metallic Foreign Body: A Case Report and Surgical Management].

Klinische Monatsblatter fur Augenheilkunde·2026
See all related articles

Related Experiment Video

Updated: Jun 12, 2026

Iris Fixation via External Pentagram Suturing
05:22

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

[Primary intrastromal iris cysts].

M Ruppenstein1, B K Straub, T Ach

  • 1Universitäts-Augenklinik Heidelberg, Heidelberg, Germany.

Klinische Monatsblatter Fur Augenheilkunde
|May 22, 2010
PubMed
Summary
This summary is machine-generated.

Primary intrastromal iris cysts, though rare in adults, can cause vision loss. These cysts originate from surface ectoderm, challenging previous assumptions about their cellular origin.

More Related Videos

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
06:15

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
10:14

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

Related Experiment Videos

Last Updated: Jun 12, 2026

Iris Fixation via External Pentagram Suturing
05:22

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
06:15

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
10:14

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

Area of Science:

  • Ophthalmology
  • Histopathology
  • Cell Biology

Context:

  • Iris cysts are uncommon, often secondary to trauma or surgery.
  • Primary intrastromal iris cysts are rare, typically diagnosed in children, and can impact vision.
  • Adult cases of primary intrastromal iris cysts are exceptionally rare.

Purpose:

  • To present two cases of primary intrastromal iris cysts in a child and an adult.
  • To investigate the cellular origin of these rare cysts using histological, electron-microscopic, and immunohistochemical methods.

Summary:

  • Two patients, a 5-year-old boy and a 65-year-old woman, presented with symptomatic primary intrastromal iris cysts affecting the optical axis.
  • Surgical removal and subsequent analysis revealed epithelial structures consistent with surface ectodermal origin.
  • Immunohistochemistry confirmed epithelial markers and ruled out mesenchymal or neuroectodermal origins.

Impact:

  • Demonstrates that primary intrastromal iris cysts can occur in adults and cause visual symptoms.
  • Provides strong evidence supporting a surface ectodermal origin for primary intrastromal iris cysts.
  • Contributes to understanding the cellular basis of rare iris pathologies.