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Updated: Jun 12, 2026

Gene Transfer for Ischemic Heart Failure in a Preclinical Model
Published on: May 15, 2011
[Modes of infusion provision of myocardial revascularization on the working heart]
Abstract:
The paper deals with the study of the impact of liberal (traditional) and conservative (restrictive) infusion strategy on oxygen transport, central hemodynamics, and vascular tone during myocardial revascularization on the working heart. Two patient groups intraoperatively received different infusion volumes under the control of central hemodynamic parameters by a PICCO PLUS system (Pulsion, Germany) and oxygen transport. There were no significant differences in the major parameters between the groups. However, after applying the conservative strategy, postoperative pulmonary compliance and artificial ventilation duration were less than those after liberal infusion strategy. Based on the findings, it is concluded that the restrictive infusion strategy is restrictive during myocardial revascularization on the working heart.
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