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Whole Genome Sequencing for Rapid Characterization of Rabies Virus Using Nanopore Technology
Published on: August 18, 2023
Rabies post-exposure prophylaxis in travellers returning from Bali, Indonesia, November 2008 to March 2010.
1Hôpital Nord, Assistance Publique-Hôpitaux de Marseille, Marseille, France. philippe.gautret@club-internet.fr
Summary
Bali is a growing concern for rabies risk among travelers. Since 2008, monkey exposures, not dog bites, have been the primary cause of rabies post-exposure prophylaxis (PEP) for visitors.
Area of Science:
- Travel Medicine
- Infectious Diseases
- Public Health
Background:
- The 2008 Bali rabies outbreak highlighted the need for surveillance of rabies risk in popular tourist destinations.
- GeoSentinel and EuroTravNet monitor health issues in international travelers, providing crucial data on disease exposure.
Purpose of the Study:
- To assess the epidemiology of rabies post-exposure prophylaxis (PEP) among travelers returning from Bali.
- To identify the primary animal sources of exposure leading to PEP in this demographic.
Main Methods:
- Analysis of data from GeoSentinel and EuroTravNet network clinics from 2008 onwards.
- Focus on patients presenting for rabies PEP after travel to Bali.
- Categorization of animal exposures (e.g., monkey, dog) leading to PEP.
Main Results:
- 45 travelers received rabies PEP after visiting Bali, comprising 12.6% of all PEP cases in the network.
- Bali is identified as an emerging destination for travelers requiring rabies PEP.
- The majority of animal exposures were due to monkeys, rather than dogs.
Conclusions:
- Travelers to Bali face a significant risk of rabies exposure, primarily from monkeys.
- Public health messaging and animal bite prevention strategies in Bali should prioritize monkey encounters.
- Continued surveillance is essential to monitor rabies risk in popular tourist destinations.
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