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Lupus miliaris disseminatus faciei: a case report
Tiago Esteves1, Anabela Faria, Rubina Alves
1Department of Dermatology, Hospital Central do Funchal, Funchal, Madeira, Portugal. tiago.castroesteves@gmail.com
Dermatology Online Journal
|May 25, 2010
Summary
Lupus miliaris disseminatus faciei (LMDF) is a rare facial rash. This case study shows successful treatment with minocycline and systemic steroids, supporting LMDF as a distinct inflammatory condition.
Area of Science:
- Dermatology
- Histopathology
Background:
- Lupus miliaris disseminatus faciei (LMDF) is an uncommon chronic inflammatory dermatosis.
- Characterized by facial papules, LMDF's etiology remains debated, with historical links to tuberculosis and rosacea.
- This case explores LMDF as a distinct entity.
Observation:
- A 33-year-old man presented with asymptomatic, red-brown, dome-shaped facial papules evolving over one year.
- Skin biopsy revealed epithelioid granuloma with central necrosis and giant cells.
- Initial presentation showed normal chest X-ray, lab results, and a negative Mantoux test.
Findings:
- Treatment with minocycline yielded partial improvement, with residual forehead papules.
- Subsequent treatment with systemic steroids led to significant lesion resolution.
- Histopathological findings, while granulomatous, did not support a tuberculous origin.
Implications:
- The case supports LMDF as a distinct dermatological entity, separate from lupus vulgaris or tuberculids.
- Successful treatment with antibiotics and steroids highlights potential therapeutic strategies.
- Further research is needed to fully elucidate the pathogenesis and optimal management of LMDF.
