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Updated: Jun 12, 2026

Biofunctionalization of Magnetic Nanomaterials
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Biofunctionalization of Magnetic Nanomaterials

Published on: July 16, 2020

Tailor-made biofunctionalized nanoparticles using layer-by-layer technology.

Hagar I Labouta1, Marc Schneider

  • 1Pharmaceutical Nanotechnology, Saarland University, Saarbrücken, Germany.

International Journal of Pharmaceutics
|May 25, 2010
PubMed
Summary

The layer-by-layer (LBL) technique enables precise control over nanoparticle coatings for advanced applications. This method offers significant potential in pharmaceutical and biomedical fields due to its versatility.

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Area of Science:

  • Materials Science
  • Nanotechnology
  • Surface Chemistry

Background:

  • The layer-by-layer (LBL) technique is established for nanofilm formation on surfaces and microparticles.
  • Surface functionalization of nanoparticles using LBL is a recent, high-interest research area.

Purpose of the Study:

  • To provide an overview of recent achievements in applying LBL technology to nanoparticles.
  • To highlight potential pharmaceutical and biomedical applications of LBL-functionalized nanoparticles.
  • To discuss future research directions in this field.

Main Methods:

  • Layer-by-layer (LBL) assembly for controlled nanofilm deposition.
  • Application of LBL on micro-sized colloidal particles and nanoparticles.
  • Analysis of shell composition, charge, and thickness control.

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Last Updated: Jun 12, 2026

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Main Results:

  • LBL technique allows fine control over nanoparticle shell properties.
  • Demonstrated versatility of LBL for creating functionalized nanoparticles.
  • Identified numerous potential applications in medicine and pharmaceuticals.

Conclusions:

  • LBL is a powerful technique for nanoparticle surface modification.
  • Significant advancements have been made in LBL applications for nanoparticles.
  • Further research is warranted to fully explore the potential of LBL-functionalized nanoparticles.