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Further evidence supporting the association between 5HTR2C gene and bipolar disorder
Marianna Mazza1, Laura Mandelli, Giovanni Martinotti
1Department of Psychiatry, Catholic University, Gemelli Hospital, Rome, Italy.
Abstract:
Three 5HTR2C polymorphisms were investigated in bipolar (BD) spectrum disorders. The functional rs6318 G (Cys) allele was more frequent in BD patients than in controls (P=0.0036). Thus, 5HTR2C may have a role in BD. Further investigation is required to understand its involvement in co-morbidity for substance use disorders (SUDs).
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