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Related Concept Videos

Treatment Resistant Cancers02:56

Treatment Resistant Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
Treatment Resistent Cancers02:56

Treatment Resistent Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...

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Updated: Jun 12, 2026

Therapeutic Massage for Psychological Well-being in Geriatric Oncology
03:59

Therapeutic Massage for Psychological Well-being in Geriatric Oncology

Published on: May 22, 2026

[Comorbidity oriented oncology - an overview].

Ralph Simanek1, Michael Wuensch, Roland Edlinger

  • 15. Medizinische Abteilung mit Onkologie und Palliativstation, Krankenhaus Hietzing, Wien, Austria.

Wiener Klinische Wochenschrift
|May 27, 2010
PubMed
Summary
This summary is machine-generated.

The Comprehensive Geriatric Assessment (CGA) is vital for older cancer patients, evaluating health beyond age. It guides personalized treatment by assessing comorbidities, function, and overall well-being.

Related Experiment Videos

Last Updated: Jun 12, 2026

Therapeutic Massage for Psychological Well-being in Geriatric Oncology
03:59

Therapeutic Massage for Psychological Well-being in Geriatric Oncology

Published on: May 22, 2026

Area of Science:

  • Geriatric Oncology
  • Cancer Care for Elderly Patients

Context:

  • Aging populations lead to more elderly cancer patients.
  • Chronological age is an insufficient predictor of health status in older adults.
  • Comorbidities and functional impairments significantly impact cancer treatment decisions and outcomes.

Purpose:

  • To highlight the importance of Comprehensive Geriatric Assessment (CGA) in managing elderly cancer patients.
  • To emphasize the need for individualized treatment planning based on a holistic health appraisal.
  • To inform oncologists about specific considerations for systemic antineoplastic therapy in older adults.

Summary:

  • Comprehensive Geriatric Assessment (CGA) evaluates nutritional, cognitive, psychological, and social factors, alongside medical conditions and medications.
  • The Society of Geriatric Oncology (SIOG) recommends CGA for cancer patients over seventy.
  • Organ-specific insufficiencies (renal, hepatic, cardiac, bone marrow) necessitate treatment adjustments, with available supportive therapies.

Impact:

  • CGA enables personalized cancer treatment strategies for elderly patients, improving care quality.
  • Early integration of palliative care specialists is recommended alongside oncological treatment.
  • Optimized treatment plans considering geriatric-specific factors can lead to better patient outcomes.