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PET and SPECT imaging of the NMDA receptor system: an overview of radiotracer development

F Sobrio1, G Gilbert, C Perrio

  • 1CEA, I2BM, CI-NAPS, LDM-TEP, Centre Cyceron, Caen, France. sobrio@cyceron.fr

Mini Reviews in Medicinal Chemistry
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Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
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Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...