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Published on: November 7, 2018
[Phenols from Euphorbia humifusa]
Ying Tian1, Limin Sun, Xiqiao Liu
1Department of Pharmaceutical Chemistry, Institute of Radiation Medicine, Academy of Military Medical Science, Beijing 100850, China.
Abstract:
The investigation on the herbal of Euphorbia humifusa Wild. was carried out to find its anti-HBV constituents. The isolation and purification were performed by chromatography such as macroporous resin, polyamide, Sephadex LH-20, MCI GEL CHP 20P and so on. Based on the spectral analysis, seven phenols were identified as brevifolin (1), brevifolin carboxylic acid (2), methyl brevifolincarboxylate (3), phyllanthussin E methyl ester (4), sanguisorbic acid dilactone (5), 3,3'-2-di-O-methyl ellagic acid (6), ellagic acid (7). Among them, Compounds 2-6 were isolated from this plant for the first time.
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