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Optical Coherence Tomography: Imaging Mouse Retinal Ganglion Cells In Vivo
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Optic disc abnormalities - diagnosis, evolution and influence on visual acuity.

Sonja Cekić1, Gordana Stanković-Babić, Zlatica Visnjić

  • 1Department for retinal disorders, Eye Clinic, Clinic Centre Nis, Bulevar Dr Zorana Djindjića 48, Nis, Serbia.

Bosnian Journal of Basic Medical Sciences
|May 29, 2010
PubMed
Summary

Congenital optic disc abnormalities vary in severity and presentation, often diagnosed in childhood. Early detection and specific imaging are crucial for managing potential vision loss and associated conditions.

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Area of Science:

  • Ophthalmology
  • Pediatric Ophthalmology
  • Medical Imaging

Background:

  • Congenital optic disc abnormalities are relatively common, with unknown etiologies for many.
  • These conditions can range from asymptomatic to severely impacting visual acuity.
  • They may present unilaterally or bilaterally, often in preschool-aged children with strabismus.

Purpose of the Study:

  • To present a series of cases involving diverse congenital optic disc abnormalities.
  • To highlight the diagnostic challenges and management considerations for these conditions.

Main Methods:

  • Case study presentation.
  • Review of diagnostic procedures including fluorescein angiography and ultrasonography.
  • Ophthalmologic examination findings.

Main Results:

  • Optic disc abnormalities discussed include optic disc drusen, congenital optic disc coloboma, hypoplasia of the optic disc, optic disc pit, and myelinated nerve fibers (Mellin's fibers).
  • Some conditions, like optic disc drusen and myelinated nerve fibers, may be detected during routine exams but pose diagnostic challenges.
  • Potential complications include serous retinal detachment, optic disc atrophy, subretinal neovascularization, retinal detachment, retinoschisis, macular edema, choroidal neovascularization, and lipid exudation.

Conclusions:

  • Congenital optic disc abnormalities require careful diagnosis and monitoring.
  • Associated ocular and central nervous system malformations should be considered.
  • Advanced imaging techniques are vital for accurate diagnosis of certain optic disc anomalies.