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Updated: Jun 12, 2026

Measuring Local Anaphylaxis in Mice
Published on: October 14, 2014
Anaphylaxis with angioedema by rocuronium during induction of general anesthesia -A case report-
Won Ju Jeong1, Woon Young Kim, Joo Hyung Son
1Department of Anesthesiology and Pain Medicine, Korea University College of Medicine, Ansan Hospital, Ansan, Korea.
Abstract:
Perioperative anaphylaxis is characterized by severe respiratory and cardiovascular manifestations. Correct management of anaphylaxis during anaesthesia requires a multidisciplinary approach with prompt recognition and treatment of the acute event by the attending anesthesiologist. A 34-year-old woman was scheduled to undergo endo venous laser therapy of varicose veins. She had no history of allergies and had never undergone general anesthesia. General anesthesia was induced with propofol and rocuronium bromide. Approximately three minutes after rocuronium administration, hypotension and tachycardia developed and angioedema around the eyelids and skin rashes and urticaria appeared. The patient received ephedrine and hydrocortisone with hydration. After achieving stable vital signs and symptom relief, surgery was performed without complications. A postoperative skin dermal test performed to identify the agent responsible revealed a positive skin test for rocuronium.
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