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Published on: November 8, 2015
[Spectrophotometric and HPLC evaluation of ceftazidime stability]
B Palade1, B Cioroiu, Doina Lazăr
1Universitatea de Medicină şi Farmacie Gr. T. Popa Iaşi, Facultatea de Farmacie, Disciplina de Analiza Medicamentelor.
Unlabelled:
In this paper we followed up the stability of ceftazidime, raw material used in drug industry. Matherials and methods: We used three spectrophotometric methods based on ceftazidime property to form complexes with p-chloranilic acid (ac. p-CA), 3-methylbenzothiazolin-2-on hydrazone (MBTH) and N-(1-naphtil) etilendiamine (NEDA) and a chromatographic method (HPLC).
Results:
Our results revealed that the substances analyzed maintained minimum content allowable.
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