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Stereodifferentiation in fluorescence quenching within cholic acid aggregates
M Consuelo Cuquerella1, Jana Rohacova, M Luisa Marin
1Instituto de Tecnología Química (UPV-CSIC), Universidad Politécnica de Valencia, Consejo Superior de Investigaciones Científicas, Avenida de los Naranjos s/n. 46022, Valencia, Spain.
Abstract:
Two cholic acid (ChA) analogues, containing a 4-nitrobenzo-2-oxa-1,3-diazole (NBD) moiety at C-3, were incorporated into ChA aggregates and submitted to fluorescence quenching by the two enantiomers of several tryptophan derivatives. In all cases, a significant stereodifferentiation was observed; the most remarkable effect was found when comparing the 3alpha and the 3beta diastereomers.

