Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Assessment of Diffusion and Perfusion01:17

Assessment of Diffusion and Perfusion

Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this principle...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An automated quantitative report for multiple sclerosis using only 3D T2-fluid-attenuated inversion recovery MRI.

Neuroradiology·2026
Same author

Structure-function multilayer network integration and cognition in multiple sclerosis.

Network neuroscience (Cambridge, Mass.)·2026
Same author

Selecting the optimal keyhole approach for internal carotid and middle cerebral artery aneurysms. Anatomical comparison of transorbital, lateral supraorbital and minipterional routes with clinical implications.

Acta neurochirurgica·2026
Same author

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS.

Annals of clinical and translational neurology·2026
Same author

Brain Age Estimation on T2-FLAIR Scans for Application to Multiple Sclerosis.

Human brain mapping·2026
Same author

A Direct Auditory Subcortical Route to the Amygdala Associated with Fear in Humans.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2026

Related Experiment Video

Updated: Jun 12, 2026

Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging
15:48

Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging

Published on: December 15, 2014

Analysis of new diffusion tensor imaging anisotropy measures in the three-phase plot.

Ferran Prados1, Imma Boada, Alberto Prats-Galino

  • 1Graphics and Imaging Laboratory, University of Girona, 17071 Girona, Spain.

Journal of Magnetic Resonance Imaging : JMRI
|June 1, 2010
PubMed
Summary

New diffusion tensor imaging measures, Compositional Kullback-Leibler (KLA), better distinguish white and gray matter than fractional anisotropy (FA). KLA shows promise for segmenting brain tissues in diffusion imaging.

More Related Videos

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
09:33

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Published on: July 28, 2013

Diffusion Imaging in the Rat Cervical Spinal Cord
10:46

Diffusion Imaging in the Rat Cervical Spinal Cord

Published on: April 7, 2015

Related Experiment Videos

Last Updated: Jun 12, 2026

Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging
15:48

Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging

Published on: December 15, 2014

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
09:33

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Published on: July 28, 2013

Diffusion Imaging in the Rat Cervical Spinal Cord
10:46

Diffusion Imaging in the Rat Cervical Spinal Cord

Published on: April 7, 2015

Area of Science:

  • Neuroimaging
  • Diffusion Tensor Imaging (DTI)
  • Biomedical Engineering

Background:

  • Diffusion Tensor Imaging (DTI) is crucial for analyzing white matter architecture.
  • Quantifying diffusion anisotropy is key to understanding white matter integrity.
  • Existing measures like Fractional Anisotropy (FA) have limitations in differentiating certain brain tissues.

Purpose of the Study:

  • To evaluate novel diffusion anisotropy measures derived from Hellinger divergences and compositional data distances.
  • To compare the sensitivity of new measures against classic metrics like FA and Relative Anisotropy (RA).
  • To assess the utility of these measures in detecting white and gray matter changes.

Main Methods:

  • Diffusion anisotropy measures were derived using Hellinger divergences and compositional data distances.
  • New measures were compared with Fractional Anisotropy (FA) and Relative Anisotropy (RA).
  • Evaluation utilized the three-phase plot (3P-plot) on human DTI data from five volunteers, focusing on white matter (WM) and gray matter (GM) regions of interest.

Main Results:

  • The Compositional Kullback-Leibler (KLA) measure demonstrated similar behavior to FA.
  • KLA exhibited superior detection of transitions between white and gray matter.
  • KLA provided better discrimination in areas with high fiber confluence.

Conclusions:

  • Compositional Kullback-Leibler (KLA) offers improved differentiation between white matter (WM) and gray matter (GM) compared to FA.
  • KLA is a promising metric for segmenting WM from GM in DTI data.
  • The findings suggest KLA's potential for enhanced neuroimaging analysis.