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Related Concept Videos

Vaccinations01:51

Vaccinations

Overview
Active versus Passive Immunity01:31

Active versus Passive Immunity

Immunity, along with the ability to limit pathogen growth to prevent significant body tissue damage, can be gained either by (1) actively developing an immune response within the individual after exposure to a pathogen or after getting vaccinated or (2) passively transferring immune components from an immune individual to one who is nonimmune. Both these forms of immunity can be found naturally and in medical practices.
Active Immunity
Active immunity refers to the resistance one develops...
Immunological Memory01:23

Immunological Memory

Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature is...
Immunodeficiency Diseases01:25

Immunodeficiency Diseases

Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency disorders...
Smallpox01:24

Smallpox

Smallpox is a severe contagious disease caused by the Variola major virus, a double-stranded DNA member of the Poxviridae family.Variola major transmission occurs primarily via inhalation of virus-laden droplets or direct contact with infectious scabs. The incubation period averages approximately seven days, although it may range from 7 to 17 days depending on the inoculum and host factors.Clinically, the prodromal phase is marked by an abrupt onset of high fever, malaise, headache, and myalgia.
Development of Immunocompetence01:22

Development of Immunocompetence

The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...

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Related Experiment Video

Updated: Jun 12, 2026

Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen
07:44

Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen

Published on: May 12, 2023

Increasing immunization coverage.

Lawrence D Hammer, Edward S Curry, Allen D Harlor

    Pediatrics
    |June 2, 2010
    PubMed
    Summary
    This summary is machine-generated.

    Childhood immunization rates are improving, but challenges like rising vaccine costs and misinformation persist. Continued efforts are needed to ensure universal vaccine access for all children.

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    Intranasal Immunization and Milk Collection in Studies of Maternal Immunization in New Zealand White Rabbits (Oryctolagus cuniculus)

    Published on: July 31, 2021

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    Published on: May 12, 2023

    Intranasal Immunization and Milk Collection in Studies of Maternal Immunization in New Zealand White Rabbits (Oryctolagus cuniculus)
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    Intranasal Immunization and Milk Collection in Studies of Maternal Immunization in New Zealand White Rabbits (Oryctolagus cuniculus)

    Published on: July 31, 2021

    Area of Science:

    • Pediatric Public Health
    • Vaccinology
    • Health Policy

    Background:

    • The American Academy of Pediatrics has advocated for universal childhood immunization since 1977.
    • Significant progress has been made in immunization coverage, with 90% of children aged 19-35 months receiving key vaccines.
    • However, the Healthy People 2010 goal for full vaccine series completion has not been met, particularly for adolescents.

    Framework:

    • The study reviews historical policy statements and current immunization coverage data.
    • It identifies emerging challenges impacting the achievement of universal immunization goals.
    • Focuses on the need for continued progress and strategies to overcome obstacles.

    Implementation:

    • Challenges include increased vaccine costs, inadequate practitioner reimbursement, supply chain disruptions, and the spread of vaccine misinformation.
    • The rise of the antivaccination movement, amplified by the internet, poses a significant threat.
    • Collaboration among healthcare providers, manufacturers, payers, media, and government is crucial.

    Implications:

    • Pediatricians must advocate for timely immunization for all eligible children.
    • Effective communication with parents regarding vaccine safety and efficacy is essential.
    • Addressing misinformation and ensuring vaccine availability and affordability are critical for public health.