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A simple fluorescent strategy for in situ evaluation of cell surface carbohydrate with a quantum dot-lectin nanoprobe
1Key Laboratory of Analytical Chemistry for Life Science (Ministry of Education of China), Department of Chemistry, Nanjing University, Nanjing 210093, P. R. China.
The Analyst
|June 2, 2010
Abstract:
A simple and rapid fluorescent method was developed for the in situ evaluation of cell surface carbohydrate by homogeneous specific recognition of a quantum dot-lectin nanoprobe to mannosyl groups on the cell surface. The strategy was further used for dynamically monitoring the alteration of cell surface carbohydrate expression in response to drugs.
