Jove
Visualize
Contact Us

Related Concept Videos

Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
Computed Tomography01:10

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Overview of Microscopy Techniques01:22

Overview of Microscopy Techniques

The early pioneers of microscopy opened a window into the invisible world of microorganisms. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes that leveraged nonvisible light, such as fluorescence microscopy that uses an ultraviolet light source and electron microscopy that uses short-wavelength electron beams. These advances significantly improved magnification, image resolution, and contrast. By comparison, the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Computational aberration correction enables full-thickness retinal imaging with adaptive optics optical coherence tomography.

Biocybernetics and biomedical engineering·2026
Same author

Spatio-temporal optical coherence imaging and tomography for <i>in vivo</i> applications.

Journal of biomedical optics·2026
Same author

Single-shot, depth-encoded multiplexed OCT for multi-spot tracking of induced transient corneal dynamics.

Biomedical optics express·2026
Same author

Effect of laser-beam diameter on the visibility of two-photon stimuli.

Optics letters·2026
Same author

Correction to "High-Throughput Monitoring of Bacterial Cell Density in Nanoliter Droplets: Label-Free Detection of Unmodified Gram-Positive and Gram-Negative Bacteria".

Analytical chemistry·2025
Same author

Photopic flicker optoretinography captures the light-driven length modulation of photoreceptors during phototransduction.

Proceedings of the National Academy of Sciences of the United States of America·2025
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 12, 2026

Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography
08:50

Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography

Published on: February 9, 2019

High-speed optical coherence tomography: basics and applications.

Maciej Wojtkowski1

  • 1Institute of Physics, Nicolaus Copernicus University, ul. Grudziadzka 5, 87-100, Torun, Poland. maciej.wojtkowski@fizyka.umk.pl

Applied Optics
|June 3, 2010
PubMed
Summary
This summary is machine-generated.

Ultrahigh-speed optical coherence tomography (OCT) now enables rapid in vivo 3D imaging. Advances in Fourier-domain OCT offer new biomedical imaging possibilities, including functional imaging for pathology differentiation.

More Related Videos

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)
12:22

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)

Published on: August 4, 2018

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
08:22

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Published on: January 12, 2022

Related Experiment Videos

Last Updated: Jun 12, 2026

Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography
08:50

Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography

Published on: February 9, 2019

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)
12:22

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)

Published on: August 4, 2018

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
08:22

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Published on: January 12, 2022

Area of Science:

  • Biomedical Imaging
  • Optical Engineering

Background:

  • Optical Coherence Tomography (OCT) has seen rapid advancements in the last decade.
  • Development of Fourier-domain detection techniques has enabled ultrahigh-speed OCT instruments.

Purpose of the Study:

  • To discuss the fundamental limitations and advantages of time-domain and Fourier-domain OCT detection methods.
  • To review the progress of high-speed OCT instruments and their impact on imaging applications.
  • To demonstrate new perspectives on functional imaging using state-of-the-art high-speed OCT technology.

Main Methods:

  • Discussion of time-domain and Fourier-domain interferometric detection methods.
  • Review of ultrahigh-speed optical coherence tomography instrument development.
  • Demonstration of functional imaging capabilities.

Main Results:

  • Ultrahigh-speed OCT instruments achieve speeds exceeding 100,000 A-scans/s.
  • High-speed imaging allows for in vivo 3D volumetric reconstructions within reasonable timeframes.
  • Functional imaging shows potential for differentiating tissue pathologies based on metabolic or functional responses.

Conclusions:

  • High-speed OCT technology overcomes previous limitations, enabling large-scale in vivo 3D imaging.
  • Novel applications and research fields in biomedical imaging are opened by high-speed OCT.
  • Functional imaging with high-speed OCT presents promising avenues for disease diagnosis and research.