Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hepatitis01:25

Hepatitis

Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver. The...
Viral Hepatitis I: Introduction01:28

Viral Hepatitis I: Introduction

Viral hepatitis is an inflammatory condition of the liver caused by infection with hepatotropic viruses, most commonly hepatitis A, B, C, D, and E. Despite variations in structure and transmission, all viruses mentioned infect hepatocytes and provoke immune responses that can hinder liver function. Additionally, some non-hepatotropic viruses can also lead to hepatic inflammation.Hepatitis A VirusHepatitis A virus (HAV) is transmitted through the fecal–oral route, typically by ingestion of food...
Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
Probability Laws01:49

Probability Laws

Overview
Transcytosis of IgG01:15

Transcytosis of IgG

Transcytosis is the process in which molecules are internalized by endocytosis, transported across the cell, and released through exocytosis from the opposite end of the cell. Molecules such as insulin, immunoglobulins, and certain nutrients are transferred through the recycling endosomes by recycling and transcytosis.
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...
Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test01:22

Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test

In clinical practice, the direct measurement of hepatic blood flow to evaluate liver function presents significant challenges due to the intricate and specialized nature of the necessary techniques. Consequently, healthcare professionals often rely on empirical estimates derived from thorough patient examinations and liver function tests to gauge liver health. Among the tools at their disposal, the Child–Pugh and MELD scoring systems stand out for their ability to categorize and assess the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Epidemiological patterns of acute respiratory illnesses in a tertiary center in Riyadh, Saudi Arabia.

Annals of Saudi medicine·2026
Same author

Clinical Characteristics and Outcomes of Gastrointestinal Tuberculosis in Saudi Arabia: A 10-year Retrospective Cohort Study.

International journal of mycobacteriology·2026
Same author

Towards Predicting Length of Stay and Identification of Cohort Risk Factors Using Self-Attention-Based Transformers and Association Mining: COVID-19 as a Phenotype.

Diagnostics (Basel, Switzerland)·2023
Same author

Ten-year experience of Q fever endocarditis in a tertiary cardiac center in Saudi Arabia.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases·2019
Same author

Salmonella typhimurium epidural empyema in an HIV-infected patient.

Infectious disease reports·2014
Same author

Ischemic pancolitis: recognizing a rare form of acute ischemic colitis.

La Tunisie medicale·2011

Related Experiment Video

Updated: Jun 12, 2026

Real-Time Polymerase Chain Reaction-Based Detection and Quantification of Hepatitis B Virus DNA
04:11

Real-Time Polymerase Chain Reaction-Based Detection and Quantification of Hepatitis B Virus DNA

Published on: December 15, 2023

[Hepatitis B and pregnancy].

Dalenda Arfaoui1, Meriem Fkih, Alaa Eddine Hafsa

  • 1Service de gastroentérologie, CHU Sahloul- Sousse, Tunis.

La Tunisie Medicale
|June 3, 2010
PubMed
Summary
This summary is machine-generated.

Hepatitis B virus can transmit from mother to child, posing risks of liver disease. Serovaccination of newborns effectively prevents this vertical transmission, safeguarding infant health.

More Related Videos

Modeling Hepatitis B Virus Infection in Non-Hepatic 293T-NE-3NRs Cells
09:02

Modeling Hepatitis B Virus Infection in Non-Hepatic 293T-NE-3NRs Cells

Published on: June 5, 2020

A Competent Hepatocyte Model Examining Hepatitis B Virus Entry through Sodium Taurocholate Cotransporting Polypeptide as a Therapeutic Target
11:34

A Competent Hepatocyte Model Examining Hepatitis B Virus Entry through Sodium Taurocholate Cotransporting Polypeptide as a Therapeutic Target

Published on: May 10, 2022

Related Experiment Videos

Last Updated: Jun 12, 2026

Real-Time Polymerase Chain Reaction-Based Detection and Quantification of Hepatitis B Virus DNA
04:11

Real-Time Polymerase Chain Reaction-Based Detection and Quantification of Hepatitis B Virus DNA

Published on: December 15, 2023

Modeling Hepatitis B Virus Infection in Non-Hepatic 293T-NE-3NRs Cells
09:02

Modeling Hepatitis B Virus Infection in Non-Hepatic 293T-NE-3NRs Cells

Published on: June 5, 2020

A Competent Hepatocyte Model Examining Hepatitis B Virus Entry through Sodium Taurocholate Cotransporting Polypeptide as a Therapeutic Target
11:34

A Competent Hepatocyte Model Examining Hepatitis B Virus Entry through Sodium Taurocholate Cotransporting Polypeptide as a Therapeutic Target

Published on: May 10, 2022

Area of Science:

  • Hepatology
  • Virology
  • Immunology

Context:

  • Chronic Hepatitis B infection is a significant global health concern, potentially leading to severe liver conditions like cirrhosis and hepatocellular carcinoma.
  • In women, Hepatitis B virus (HBV) poses a risk not only to their own health but also for transmission to partners and offspring.

Purpose:

  • This review critically analyzes the mechanisms driving mother-to-child transmission of Hepatitis B virus.
  • It further examines the potential consequences of such transmissions for both the infant and public health.

Summary:

  • Hepatitis B virus transmission occurs via sexual contact in low-prevalence regions and perinatally or in early childhood in moderate to high-prevalence areas.
  • In Tunisia, Hepatitis B surface antigen (HBsAg) prevalence among pregnant women is 3-4%, with a high maternal-infant contamination risk (20-90%) dependent on maternal viral load.
  • While serovaccination of newborns is a primary preventive measure, antiviral therapy (e.g., lamivudine) in late pregnancy for women with high viral loads is being explored to reduce transmission, though its definitive role requires further clarification.

Impact:

  • Implementing effective preventive strategies, such as universal newborn serovaccination, is crucial for reducing the burden of chronic Hepatitis B.
  • Further research into antiviral therapies during pregnancy may offer additional protection for infants born to mothers with high viral loads.
  • Understanding transmission dynamics is vital for targeted public health interventions in regions with significant Hepatitis B prevalence.