Nutritional recovery with rice bran did not modify energy balance and leptin and insulin levels
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Updated: Jun 12, 2026

Assessment of the Metabolic Effects of Isocaloric 2:1 Intermittent Fasting in Mice
Published on: November 27, 2019
Maria Salete F Martins1, Lila M Oyama, Marcia Q Latorraca
1Universidade Federal de Mato Grosso, Cuiabá, MT, Brasil. msfm@terra.com.br <msfm@terra.com.br>
Objective:
To investigate the effect of nutritional recovery with rice bran on energy balance, leptin and insulin levels.
Methods:
Weaned Wistar rats were fed on a 17% (Control - C) or 0.5% (Aproteic - A) protein diet for 12d. After this, rats were kept on a C diet (C) or recovered with control (Recovered Control - RC) or control plus recovered rice bran diet (Recovered Rice Bran - RRB).
Results:
Despite the increased food intake, group A exhibited lower carcass fat associated to low serum leptin. RRB and RC groups showed lower carcass weight and energy intake and expenditure. Energy expenditure was positively associated with food intake and carcass weight. Negative correlations between HOMA-IR and energy expenditure and energy intake were observed.
Conclusion:
Nutritional recovery with rice bran did not modify energy balance, leptin and insulin levels.
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