Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Blood Studies for Cardiovascular System III: Serum Lipid Profile01:25

Blood Studies for Cardiovascular System III: Serum Lipid Profile

Understanding serum lipids is crucial for maintaining cardiovascular health and preventing heart disease and stroke.
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
Overview of Lipid Metabolism01:24

Overview of Lipid Metabolism

Lipid metabolism is a crucial process in the human body that involves the synthesis and degradation of lipids. This process is essential for energy production, cell membrane formation, and hormone production, among other functions.
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
Lipids: Dietary Sources and Requirements01:18

Lipids: Dietary Sources and Requirements

Lipids are an essential component of a balanced human diet. Triglycerides, which make up the majority of dietary lipids, are found in both saturated fats—commonly present in meat, dairy products, and certain tropical plants like coconut, and hydrogenated oils such as margarine and baking shortenings (trans fats)—and unsaturated fats, which are abundant in seeds, nuts, olive oil, and most vegetable oils. The main sources of cholesterol include egg yolks, various meats and organ meats, shellfish,...
Cholesterol: Significance and Regulation01:29

Cholesterol: Significance and Regulation

Although not a source of energy, cholesterol plays a significant role as a foundational structure for bile salts, steroid hormones, and vitamin D, as well as being a crucial component of plasma membranes. Approximately 15% of blood cholesterol is derived from our diet, with the remainder synthesized from acetyl CoA by the liver and intestines. Cholesterol is eliminated from the body through its conversion into bile salts, which are eventually discarded in the feces.
Considering cholesterol and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hybridization of isatin and benzoxazolinone via a diethyl spacer: a new scaffold for breast cancer drug discovery.

Future medicinal chemistry·2026
Same author

Variability in diagnostic and therapeutic decision-making for endodontic-periodontal lesions: evidence from a cross-sectional study.

Frontiers in public health·2026
Same author

Assessment of clinical readiness, knowledge and attitude, regarding Basic Life Support (BLS) and cardiopulmonary resuscitation (CPR) skill among dentists practicing in Saudi Arabia.

PeerJ·2026
Same author

Examiner stratification reveals clinically relevant variability in large language model answers to endodontic patient questions.

Frontiers in medicine·2026
Same author

Tuning the size of quantum dots to enhance charge transfer and photocatalytic CO<sub>2</sub> reduction.

RSC advances·2026
Same author

Assessment of dental pain and its association with dental anxiety and oral health-related quality of life.

Acta odontologica Scandinavica·2026
Same journal

Predictors of Altmetric Score in Top-Cited Orthopaedic Articles: A Bibliometric Analysis.

JPMA. The Journal of the Pakistan Medical Association·2026
Same journal

Carbon footprint of waste generated in orthopaedic cases in Pakistan: a pilot descriptive study.

JPMA. The Journal of the Pakistan Medical Association·2026
Same journal

Enhancing quotation accuracy assessment with Chatpdf - a game-changer for a century-old conundrum.

JPMA. The Journal of the Pakistan Medical Association·2026
Same journal

Barriers to implementing simulation-based surgical training for improving quality and safety in developing countries: A short communication.

JPMA. The Journal of the Pakistan Medical Association·2026
Same journal

Intraoperative Adverse Event Reporting in Gastrointestinal Cancer Surgery: A Narrative Review on the Application of ClassIntra.

JPMA. The Journal of the Pakistan Medical Association·2026
Same journal

The Impact of Mortality and Morbidity Meetings on Quality Improvement and Patient Safety.

JPMA. The Journal of the Pakistan Medical Association·2026
See all related articles

Related Experiment Video

Updated: Jun 12, 2026

Disruption of the Mouse Blood-Brain Barrier by Small Extracellular Vesicles from Hypoxic Human Placentas
05:31

Disruption of the Mouse Blood-Brain Barrier by Small Extracellular Vesicles from Hypoxic Human Placentas

Published on: January 26, 2024

Relationship between leptin and lipids during pre-eclampsia.

Uzma Iftikhar1, Azhar Iqbal, Shazia Shakoor

  • 1Department of Physiology, Hamdard College of Medicine & Dentistry, Hamdard University, Karachi.

JPMA. the Journal of the Pakistan Medical Association
|June 10, 2010
PubMed
Summary
This summary is machine-generated.

Serum leptin levels in pre-eclampsia are linked to higher total cholesterol, potentially contributing to the condition's development and atherogenesis. These findings highlight a significant association in pregnant women.

More Related Videos

Influence of Emotional Factors on the Efficacy of Acupuncture Treatment for Overweight Complicated with Hyperlipidemia: A Retrospective Cohort Study
03:05

Influence of Emotional Factors on the Efficacy of Acupuncture Treatment for Overweight Complicated with Hyperlipidemia: A Retrospective Cohort Study

Published on: November 21, 2025

Related Experiment Videos

Last Updated: Jun 12, 2026

Disruption of the Mouse Blood-Brain Barrier by Small Extracellular Vesicles from Hypoxic Human Placentas
05:31

Disruption of the Mouse Blood-Brain Barrier by Small Extracellular Vesicles from Hypoxic Human Placentas

Published on: January 26, 2024

Influence of Emotional Factors on the Efficacy of Acupuncture Treatment for Overweight Complicated with Hyperlipidemia: A Retrospective Cohort Study
03:05

Influence of Emotional Factors on the Efficacy of Acupuncture Treatment for Overweight Complicated with Hyperlipidemia: A Retrospective Cohort Study

Published on: November 21, 2025

Area of Science:

  • Reproductive Medicine
  • Endocrinology
  • Cardiovascular Health

Background:

  • Pre-eclampsia is a pregnancy complication characterized by high blood pressure.
  • Altered lipid profiles and elevated leptin levels are observed in pre-eclampsia.
  • The atherogenic role of these changes in pre-eclampsia pathophysiology requires further elucidation.

Purpose of the Study:

  • To investigate the relationship between serum leptin levels and lipid profiles in women with pre-eclampsia.
  • To assess the potential atherogenic contribution of these markers to pre-eclampsia.

Main Methods:

  • A comparative cross-sectional study involving 90 primigravidas (45 with pre-eclampsia, 45 controls) in their third trimester.
  • Standardized maternal age, gestational age, height, and weight across all participants.
  • Serum leptin determined by immunoenzymometric assay; lipid profile by enzymatic colorimetric method.

Main Results:

  • Pre-eclamptic patients exhibited significantly elevated lipid profiles compared to controls.
  • Total cholesterol was significantly higher in severe pre-eclampsia versus mild cases (p < 0.01).
  • Serum leptin showed a significant positive correlation with total cholesterol in the pre-eclamptic group (p < 0.05).

Conclusions:

  • Serum leptin levels in pre-eclampsia are strongly associated with total cholesterol.
  • Rising leptin levels correlate with increasing total cholesterol and pre-eclampsia severity.
  • These alterations may stem from oxidative stress, contributing to atherogenesis and pre-eclampsia pathogenesis.