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Published on: August 23, 2024
Osteoporosis update: effective prevention and treatment
1University of Colorado at Denver and Health Sciences Center, Departments of Clinical Pharmacy and Family Medicine, 4200 E. 9 Ave., Box C-238, Denver, CO 80262-0238, USA. laura.hansen@uchsc.edu.
Expert Review of Pharmacoeconomics & Outcomes Research
|June 10, 2010
Summary
Osteoporosis affects millions over 50, with fracture prevention as the main goal. Management involves assessing risk factors, lifestyle changes, and current/future treatments for postmenopausal women.
Area of Science:
- Gerontology
- Public Health
- Endocrinology
Background:
- Osteoporosis is a significant public health concern, impacting 44 million Americans over 50.
- Fracture prevention is the primary objective in managing osteoporosis.
- Risk factors and bone mineral density are key for assessing prevention and treatment needs.
Purpose of the Study:
- To review current and future prevention and treatment strategies for postmenopausal osteoporosis.
- To highlight the importance of lifestyle modifications and adequate nutrient intake.
- To discuss challenges in optimal therapy, including adherence and cost.
Main Methods:
- Literature review of current and emerging osteoporosis management options.
- Analysis of prevention strategies: lifestyle, fall prevention, calcium, and vitamin D intake.
- Examination of existing treatments (antiresorptive, anabolic agents) and future drug development.
Main Results:
- Prevention includes lifestyle changes, fall reduction, and sufficient calcium/vitamin D.
- Current treatments involve antiresorptive and anabolic agents.
- Newer agents are being developed to enhance treatment efficacy and patient adherence.
Conclusions:
- Effective osteoporosis management requires a multifaceted approach.
- Addressing adherence and cost is crucial for optimal patient outcomes.
- Ongoing research aims to improve therapeutic options for postmenopausal osteoporosis.
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