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Related Concept Videos

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features01:24

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...
Endoscopic Studies I: Bronchoscopy and Thoracoscopy01:30

Endoscopic Studies I: Bronchoscopy and Thoracoscopy

Endoscopy is a non-surgical medical technique used to examine a person's internal organs and vessels. This lesson will focus on two types of endoscopic studies: bronchoscopy and thoracoscopy.
Bronchoscopy
Description
Bronchoscopy is a procedure that involves direct visualization of the larynx, trachea, and bronchi for diagnostic and therapeutic purposes. A flexible fiber optic or rigid bronchoscope is used to carry out the procedure. The fiber-optic bronchoscope is more frequently used due to...
Chronic Obstructive Pulmonary Disease I: Introduction01:23

Chronic Obstructive Pulmonary Disease I: Introduction

Chronic obstructive pulmonary disease is a common, preventable, and treatable respiratory disorder characterized by persistent symptoms and progressive airflow limitation. This limitation results from a combination of small-airway disease (obstructive bronchiolitis) and parenchymal destruction (emphysema), both driven by chronic inflammation from exposure to harmful particles or gases.The disease includes two main pathological entities: emphysema, marked by destruction of alveolar walls and...
Chronic Obstructive Pulmonary Disease II: Emphysema01:23

Chronic Obstructive Pulmonary Disease II: Emphysema

Emphysema, a major phenotype of chronic obstructive pulmonary disease (COPD), is characterized by irreversible destruction of alveolar walls and permanent enlargement of distal airspaces. Unlike chronic bronchitis, which primarily affects the airways, emphysema predominantly involves the lung parenchyma, where structural damage leads to airflow limitation.PathophysiologyIt most commonly results from prolonged exposure to cigarette smoke and other toxic gases, particularly cigarette smoke.
The Bronchial Tree01:23

The Bronchial Tree

The human bronchi and bronchial tree play a crucial role in the respiratory system, facilitating the exchange of oxygen and carbon dioxide. Let's delve into the intricate structure and functions of these respiratory components.
The trachea, commonly known as the windpipe, is a tube that connects the larynx (voice box) to the bronchi. At a point called the carina, it bifurcates into two primary bronchi. The right primary bronchus is wider, shorter, and more vertical than the left primary...
Chronic Obstructive Pulmonary Disease IV: Clinical Manifestations01:19

Chronic Obstructive Pulmonary Disease IV: Clinical Manifestations

Chronic Obstructive Pulmonary Disease, or COPD, is a long-term condition marked by persistent and only partially reversible airflow limitation. It involves two overlapping conditions—chronic bronchitis and emphysema—which often co-appear but differ in dominant symptoms and underlying mechanisms.Chronic Bronchitis FeaturesChronic bronchitis presents with a persistent productive cough and thick, sometimes purulent mucus due to airway inflammation, enlarged mucus glands, and goblet cell...

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Related Experiment Video

Updated: Jun 12, 2026

Human Lung Dendritic Cells: Spatial Distribution and Phenotypic Identification in Endobronchial Biopsies Using Immunohistochemistry and Flow Cytometry
11:02

Human Lung Dendritic Cells: Spatial Distribution and Phenotypic Identification in Endobronchial Biopsies Using Immunohistochemistry and Flow Cytometry

Published on: January 20, 2017

Primary endobronchial Hodgkin's disease.

Prakash R Malur1, Gajanan S Gaude, Hema B Bannur

  • 1Department of Pathology, J. N. Medical College, Belgaum, India.

Lung India : Official Organ of Indian Chest Society
|June 10, 2010
PubMed
Summary

This case study details primary pulmonary Hodgkin's disease, a rare lung cancer, presenting as an endobronchial mass. Diagnosis and successful treatment were achieved through surgical biopsy and chemotherapy.

Keywords:
Endobronchialprimarypulmonary Hodgkin's disease

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Last Updated: Jun 12, 2026

Human Lung Dendritic Cells: Spatial Distribution and Phenotypic Identification in Endobronchial Biopsies Using Immunohistochemistry and Flow Cytometry
11:02

Human Lung Dendritic Cells: Spatial Distribution and Phenotypic Identification in Endobronchial Biopsies Using Immunohistochemistry and Flow Cytometry

Published on: January 20, 2017

Substernal Thyroid Biopsy Using Endobronchial Ultrasound-guided Transbronchial Needle Aspiration
10:19

Substernal Thyroid Biopsy Using Endobronchial Ultrasound-guided Transbronchial Needle Aspiration

Published on: November 10, 2014

Area of Science:

  • Pulmonary Medicine
  • Oncology
  • Thoracic Surgery

Background:

  • Primary pulmonary Hodgkin's disease is an exceptionally rare extranodal manifestation of Hodgkin's lymphoma.
  • Endobronchial presentation of this condition is seldom documented, posing diagnostic challenges.
  • Early and accurate diagnosis is crucial for effective management of thoracic malignancies.

Purpose of the Study:

  • To present a unique case of primary pulmonary Hodgkin's disease.
  • To highlight the diagnostic pathway for an endobronchial mass.
  • To illustrate the therapeutic response to chemotherapy in this rare condition.

Main Methods:

  • Clinical presentation of an endobronchial mass.
  • Diagnostic confirmation via microscopic examination of tissue obtained through open thoracotomy and excision biopsy.
  • Treatment administered using a standard chemotherapy regimen.

Main Results:

  • Successful tissue diagnosis of primary pulmonary Hodgkin's disease was achieved.
  • The patient exhibited a positive response to the prescribed chemotherapy.
  • Surgical intervention provided both diagnostic material and initial management.

Conclusions:

  • Primary pulmonary Hodgkin's disease can present as an endobronchial mass, necessitating a high index of suspicion.
  • Open thoracotomy with excision biopsy is a viable method for definitive diagnosis.
  • Chemotherapy is an effective treatment modality for primary pulmonary Hodgkin's disease, leading to favorable patient outcomes.