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Related Concept Videos

Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure01:16

Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure

Oxygen therapy has emerged as a significant tool in enhancing the quality of life for patients suffering from pulmonary arterial hypertension (PAH). While this therapy has principally been studied on patients with significant hypoxemia, this therapeutic approach helps prevent potential organ damage and can be administered in the comfort of one's home.
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue, improving...
Antiasthma Drugs: Methylxanthines01:24

Antiasthma Drugs: Methylxanthines

Theophylline, a member of the methylxanthine class of bronchodilators, has long been used in asthma management. While its exact mechanism of action is not fully understood, it is believed to have multiple effects on various cellular processes.
Theophylline is thought to inhibit phosphodiesterase enzymes, increasing intracellular levels of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP). This rise in cAMP and cGMP concentrations stimulates cardiac function,...
Treatment for Pulmonary Arterial Hypertension: Phosphodiesterase Inhibitors01:28

Treatment for Pulmonary Arterial Hypertension: Phosphodiesterase Inhibitors

Phosphodiesterase 5 (PDE5) inhibitors are potent enzymes that function to hydrolyze cyclic nucleotides to their corresponding 5' monophosphates. Their unique biochemical properties have been applied in treating Pulmonary Arterial Hypertension (PAH).
Among the PDE5 inhibitors, sildenafil (Revatio) stands out as a competitive and selective inhibitor. It operates by elevating cellular levels of cGMP and augmenting signaling through the cGMP-PKG pathway, promoting vasodilation. Upon oral...
COPD: Management Using Bronchodilators and Corticosteroids01:26

COPD: Management Using Bronchodilators and Corticosteroids

Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
Pulmonary Hypertension: Classification and Pathogenesis01:30

Pulmonary Hypertension: Classification and Pathogenesis

Pulmonary hypertension (PH) is a severe health condition in which the mean pulmonary arterial pressure increases to 25 mmHg or more, even when the body is at rest. This high pressure in the blood vessels that transport blood from the heart to the lungs can cause various symptoms, including shortness of breath, can lead to right heart failure, and significantly affect the overall quality of life.
There are various classifications for PH, each relating to different underlying causes and also...
Treatment for Pulmonary Arterial Hypertension: Prostacyclin Receptor Agonists01:23

Treatment for Pulmonary Arterial Hypertension: Prostacyclin Receptor Agonists

Prostacyclin receptor agonists are a class of therapeutic agents integral to managing pulmonary arterial hypertension (PAH). These drugs operate by mimicking the action of prostaglandin I2, or PGI2, a naturally occurring compound in the body.
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Related Experiment Videos

Shilajit: A panacea for high-altitude problems.

Harsahay Meena1, H K Pandey, M C Arya

  • 1Herbal Medicine Division, Defence Research and Development Organization, DIBER, Field Station, Pithoragarh - 262 501, Uttarakhand, India.

International Journal of Ayurveda Research
|June 10, 2010
PubMed
Summary

Shilajit, a Himalayan herbomineral, may help prevent high-altitude problems by improving nutrient transport and immune function. This natural supplement can act as a health rejuvenator for those ascending to high altitudes.

Keywords:
Fulvic acidShilajitherbomineral drughigh-altitude problemshypoxiamineral pitchrejuvenator

Related Experiment Videos

Area of Science:

  • Altitude Medicine
  • Phytomedicine
  • Human Physiology

Background:

  • High-altitude environments pose significant health risks including hypoxia, acute mountain sickness, and severe fatigue.
  • These risks stem from low atmospheric pressure, extreme temperatures, and high solar radiation, potentially becoming life-threatening.

Purpose of the Study:

  • To investigate the potential of Shilajit as a prophylactic supplement for individuals ascending to high altitudes.
  • To evaluate Shilajit's efficacy in mitigating common high-altitude ailments and improving physiological resilience.

Main Methods:

  • Review of Shilajit's composition, including humus, organic plant matter, and fulvic acid.
  • Analysis of Shilajit's known physiological effects, such as nutrient transport and immune stimulation.
  • Exploration of its traditional use and proposed benefits for managing altitude-related stress.

Main Results:

  • Shilajit contains fulvic acid, which aids nutrient transport to deep tissues, combating fatigue and lethargy.
  • The herbomineral demonstrates potential in enhancing the body's ability to cope with high-altitude stresses.
  • Shilajit may stimulate the immune system, offering a protective effect against altitude-induced challenges.

Conclusions:

  • Shilajit can serve as a valuable supplement for individuals traveling to high-altitude regions.
  • It acts as a 'health rejuvenator,' potentially alleviating symptoms associated with altitude sickness and fatigue.
  • Further clinical studies are warranted to confirm Shilajit's efficacy and safety in preventing high-altitude problems.