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Exploring unfolding pathway of CGTase: insight from molecular dynamics simulation

Yi Fu1, Yanrui Ding, Zhiguo Chen

  • 1School of Information Technology, Jiangnam University, Wuxi 214122, China.

Rivista Di Biologia
|June 10, 2010
PubMed
Summary

Protein thermostability, crucial for enzymes like Cyclodextrin glycosyltransferase (CGTase), is achieved through structural modifications. Molecular dynamics simulations reveal uneven stability distribution and key unfolding mechanisms in CGTase.

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