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Updated: Jun 12, 2026

A Study of the Complexation of Mercury(II) with Dicysteinyl Tetrapeptides by Electrospray Ionization Mass Spectrometry
Published on: January 8, 2016
A selective chromogenic probe for mercury(II) and cyanide in aqueous buffered solution from a cycloaddition reaction
Pedro Fuertes1, Daniel Moreno, José V Cuevas
1Department of Chemistry, University of Burgos, Faculty of Science, 09001 Burgos, Spain.
Abstract:
The synthesis of some new polysulfur-nitrogen heterocycles by cycloaddition of an ynamine to bisdithiolothiazine ketothiones or dithiones is described and the interconversion between regioisomers is studied by DFT calculations, showing that the double bond isomerizes at room temperature. This series is a new selective and sensitive chromogenic probe for the naked-eye detection of mercury(II) cation and cyanide anion in buffered (HEPES 0.05 M, pH 7.14) water/acetonitrile 1:1 mixture, with sub-micromolar sensitivity, and constitutes the first example of a new class of colorimetric chemical probes for Hg(2+) and CN(-).
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