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Reactive vascular lesions treated using ethanolamine oleate sclerotherapy
Soon-Kwon Hong1, Hyun-Jae Lee, Jong-Keun Seo
1Department of Dermatology, Busan Paik Hospital, College of Medicine, Inje University, Busanjin-gu, Busan, Korea.
Ethanolamine oleate (EO) effectively treats reactive vascular lesions like pyogenic granulomas and venous lakes, achieving a 95% complete remission rate with minimal side effects. This suggests EO is a valuable therapeutic option in dermatology.
Area of Science:
- Dermatology
- Vascular Lesion Treatment
- Sclerotherapy
Background:
- Ethanolamine oleate (EO) is infrequently used in dermatology.
- It is recognized for treating various vascular lesions, including esophageal varices and varicose veins.
Purpose of the Study:
- To assess the efficacy and safety of Ethanolamine oleate (EO) for treating reactive vascular lesions.
- Investigate EO as a potential treatment for conditions like pyogenic granulomas and venous lakes.
Main Methods:
- Patients with reactive vascular lesions were treated with EO as a sclerosing agent.
- Initial treatment involved a 1:1 dilution with normal saline, with subsequent treatments adjusted based on response.
- Treatment outcomes were categorized as complete remission (CR), moderate improvement (MI), or no change, and side effects were documented.
Main Results:
- The study included 21 patients with pyogenic granulomas (16) and venous lakes (5).
- Lesion diameters ranged from 0.3 to 1.0 cm, with an average of 1.6 EO injections per patient.
- A 95% complete remission rate (20 CR, 1 MI) was observed, with only two instances of transient pain reported.
Conclusions:
- Ethanolamine oleate (EO) demonstrates excellent efficacy as a sclerosing agent for reactive vascular lesions.
- EO presents a viable alternative therapeutic option for managing vascular lesions within dermatological practice.
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