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[Mumps encephalitis in adulthood].

A Alfaro1, D Granda

  • 1Servicio de Neurología, Hospital Universitario La Fe, Valencia.

Neurologia (Barcelona, Spain)
|March 1, 1991
PubMed
Summary
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Mumps encephalitis is rare in adults, presenting with severe neurological symptoms. This case highlights its potential to mimic other serious brain infections, emphasizing the need for broader diagnostic considerations.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Virology

Background:

  • Mumps virus commonly causes viral meningitis.
  • Mumps encephalitis is rare in adults, unlike in children.
  • Distinguishing mumps encephalitis from other viral encephalitides is clinically important.

Observation:

  • A 23-year-old man presented with acute neurological decline, including severe headache, vomiting, mutism, gait disturbance, somnolence, and dystonic movements.
  • Electroencephalogram revealed diffuse slowing, and cerebrospinal fluid showed elevated protein without cells.
  • The patient experienced prolonged intellectual and motor deficits despite initial recovery.

Findings:

  • Serological tests confirmed elevated IgM mumps-specific antibodies, indicating acute mumps infection.

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  • The clinical presentation and CSF findings were consistent with encephalitis.
  • Recovery was slow, with persistent neurological sequelae.
  • Implications:

    • Mumps encephalitis should be considered in adult cases of viral encephalitis, particularly those mimicking herpes simplex encephalitis.
    • Early diagnosis and consideration of less common viral causes are crucial for appropriate patient management.
    • This case underscores the potential for mumps virus to cause severe neurological disease in adults.