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Comparative biochemical studies on steroidogenic compounds in chickens
Mohamed O T Badr1, Mohamed A Hashem, Nissreen N Gado
1Department of Clinical Pathology, Faculty of Veterinary Medicine, Zagazig University, Egypt.
Research in Veterinary Science
|June 15, 2010
Summary
Nordette and Lutofolone administration in chickens increased body weight and altered biochemical parameters. Elevated estrogen residues were found in liver and muscle tissues, indicating potential risks for chickens and consumers.
Area of Science:
- Veterinary Pharmacology
- Animal Science
- Biochemistry
Context:
- Anabolic agents are sometimes used in livestock production.
- Nordette and Lutofolone are synthetic hormones with potential growth-promoting effects.
- Assessing the impact of these agents on animal health and food safety is crucial.
Purpose:
- To investigate the effects of Nordette and Lutofolone on growth, biochemical parameters, and hormonal residues in chickens.
- To determine the persistence of these hormonal residues in edible tissues.
Summary:
- Chickens treated with Nordette or Lutofolone showed increased body weight and significant alterations in serum biochemical markers, including elevated liver enzymes and cholesterol, and reduced protein levels.
- Estrogen residues were significantly higher in liver and muscle tissues of treated chickens, with liver accumulating higher concentrations.
- Some biochemical and residue changes were still present 15 days after hormone withdrawal.
Impact:
- Anabolic agent use in poultry may pose health risks to the animals.
- Hormonal residues in chicken meat could present a risk to human consumers.
- This study highlights the need for careful regulation and monitoring of hormone use in animal agriculture.
