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The canine cognitive dysfunction rating scale (CCDR): a data-driven and ecologically relevant assessment tool.

Hannah E Salvin1, Paul D McGreevy, Perminder S Sachdev

  • 1Faculty of Veterinary Science (B19), University of Sydney, Camperdown, NSW 2006, Australia. hsal8835@uni.sydney.edu.au

Veterinary Journal (London, England : 1997)
|June 15, 2010
PubMed
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A new Canine Cognitive Dysfunction Rating Scale (CCDR) aids in diagnosing this common, under-diagnosed condition in older dogs. This validated tool helps track cognitive changes in veterinary and research settings.

Area of Science:

  • Veterinary Neurology
  • Animal Behavior

Background:

  • Canine Cognitive Dysfunction (CCD) is a prevalent, age-related neurobehavioral syndrome in dogs.
  • CCD is significantly under-diagnosed in community-dwelling canine populations.

Purpose of the Study:

  • To develop and validate a clinical rating scale for assessing Canine Cognitive Dysfunction (CCD).
  • To create a tool that is clinically useful and captures the breadth of cognitive-behavioral changes.

Main Methods:

  • Utilized data from a cross-sectional survey of 957 older dogs.
  • Employed data-driven analytical techniques to refine 27 behavioral items into a 13-item scale (CCDR).
  • Validated the CCDR on an independent sample, assessing diagnostic accuracy and reliability.

Main Results:

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  • The CCDR scale consists of 13 behavioral items, with three indicating disease severity.
  • Achieved high diagnostic accuracy (98.9%), positive predictive value (77.8%), and negative predictive value (99.3%) in an independent sample.
  • Demonstrated high test-retest reliability over two months (r=0.73, P<0.0001).

Conclusions:

  • The Canine Cognitive Dysfunction Rating Scale (CCDR) is a reliable and accurate tool for assessing CCD.
  • The CCDR can aid veterinarians in diagnosing and monitoring cognitive decline in dogs.
  • This scale is valuable for both clinical practice and research in canine cognitive aging.