Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Dementia l: Introduction01:22

Dementia l: Introduction

Dementia is an acquired, progressive syndrome characterized by a decline in multiple cognitive domains severe enough to impair daily functioning and reduce independence. Although memory loss is a central feature, the diagnosis requires additional deficits involving language, executive function, visuospatial skills, judgment, calculation, or abstract reasoning. These cognitive impairments reflect underlying neurodegenerative or vascular processes that gradually disrupt neuronal networks...
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
Dementia01:30

Dementia

Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual.
Alzheimer Disease ll: Pathophysiology01:23

Alzheimer Disease ll: Pathophysiology

Alzheimer disease involves structural changes in the brain that begin long before symptoms appear. The most distinctive features are extracellular neuritic plaques and intracellular neurofibrillary tangles.Neuritic plaques form in the cerebral cortex and around blood vessels. These plaques contain a dense core of beta-amyloid (Aβ)—a toxic protein fragment that clumps outside neurons. The core is surrounded by damaged neuronal extensions, as well as reactive astrocytes and microglia. Abnormal...
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests01:27

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
Peripheral Artery Disease IV: Nursing Management01:26

Peripheral Artery Disease IV: Nursing Management

The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses, temperature changes,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evolution of the frontal aslant tract and implications for primate vocalization and human speech.

Nature communications·2026
Same author

DECODE: An innovative tool to aid cross-linguistic neuropsychological assessment.

The Clinical neuropsychologist·2026
Same author

The status and interpretation of neuropsychological evidence: Commentary on 'No evidence yet for functional independence of verbal short-term memory and long-term verbal knowledge' by Majerus, Cowan and Oberauer (2026).

Journal of neuropsychology·2026
Same author

Graphic transmutations identify the phenomenon of meaningless pictures remembered as familiar objects.

Scientific reports·2026
Same author

When repeated presentation of visual feature bindings does and does not result in learning: Visual short-term and long-term memory are distinct but work in tandem.

Memory & cognition·2025
Same author

Bekhterev's case: Amnesia due to bi-hippocampal damage 50 years before HM.

Cortex; a journal devoted to the study of the nervous system and behavior·2025

Related Experiment Video

Updated: Jun 12, 2026

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients
07:42

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients

Published on: December 16, 2022

Dual task impairments in vascular dementia.

Kate Inasaridze1, Jennifer A Foley, Robert H Logie

  • 1Tbilisi State Medical University, Memory Clinic, Tbilisi, Georgia.

Behavioural Neurology
|June 15, 2010
PubMed
Summary

Dual-tasking impairment, the difficulty of doing two things at once, is common in Alzheimer's disease (AD). This study found similar dual-tasking difficulties in vascular dementia (VaD) patients, suggesting it may indicate pathological brain aging.

More Related Videos

Motor Dual-Tasks for Gait Analysis and Evaluation in Post-Stroke Patients
05:23

Motor Dual-Tasks for Gait Analysis and Evaluation in Post-Stroke Patients

Published on: March 11, 2021

Related Experiment Videos

Last Updated: Jun 12, 2026

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients
07:42

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients

Published on: December 16, 2022

Motor Dual-Tasks for Gait Analysis and Evaluation in Post-Stroke Patients
05:23

Motor Dual-Tasks for Gait Analysis and Evaluation in Post-Stroke Patients

Published on: March 11, 2021

Area of Science:

  • Neuroscience
  • Gerontology
  • Cognitive Psychology

Background:

  • Dual-tasking impairment is a known characteristic of Alzheimer's disease (AD).
  • It is unclear if this impairment is specific to AD or present in other dementia types, like vascular dementia (VaD).

Purpose of the Study:

  • To investigate dual-tasking abilities in patients with vascular dementia (VaD).
  • To determine if dual-tasking impairment is specific to AD or a broader indicator of pathological aging.

Main Methods:

  • Assessed 15 VaD patients and 25 healthy controls (age-matched and young) using a paper-and-pencil dual-tasking paradigm.
  • Administered measures of working and episodic memory.
  • Correlated performance with disease severity using the Mini-Mental State Examination (MMSE).

Main Results:

  • Age did not significantly affect dual-task performance.
  • VaD patients showed significant dual-tasking impairment compared to controls.
  • Memory performance was affected by age and further deteriorated in VaD patients.
  • Both dual-tasking and memory abilities correlated with disease severity (MMSE).

Conclusions:

  • Dual-tasking impairment is not exclusive to Alzheimer's disease and is present in vascular dementia.
  • Dual-tasking performance may serve as a specific indicator of pathological aging across different dementia types.