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Updated: Jun 12, 2026
Facial Nerve Surgery in the Rat Model to Study Axonal Inhibition and Regeneration
Published on: May 5, 2020
Long-term facial nerve function evaluation following surgery for large acoustic neuromas via retrosigmoid transmeatal
Xu Zhao1, Zhigang Wang, Yong Ji
1Department of Neurosurgery, the Second Hospital of Shandong University, Jinan, Shandong Province, China.
Purpose:
By evaluating the postoperative facial nerve function of large acoustic neuromas, the purpose of this study was to analyze the factors that influence the facial nerve function outcome and to explore the surgical strategy for large acoustic neuromas.
Methods:
A retrospective study of surgical outcome was performed on 89 patients with large acoustic neuromas. All operations were performed via the retrosigmoid transmeatal approach using the intraoperative electrophysiological monitoring.
Results:
Gross total resection was performed in 38 (42.7%) of the 89 patients, near total resection in 35 (39.3%), and subtotal resection in 16 (18.0%). The facial nerve was anatomically intact at the end of surgery in 83 (93.3%) patients. At 1 year after surgery, 48 (53.9%) patients had good facial nerve function (House-Brackmann (HB) Grades I-II), 23 (25.8%) patients had regular facial nerve function (HB Grades III-IV), and 18 (20.2%) patients had poor facial nerve function (HB Grades V-VI).
Conclusions:
For large acoustic neuromas, the goal of complete tumor resection and preservation of acceptable facial nerve function can be attained via the retrosigmoid transmeatal approach, using the intraoperative facial nerve monitoring. The surgical strategy of near total resection is indicated for the large acoustic neuromas with severe adherence or inclusion in order to preserve facial nerve function.
