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Updated: Jun 12, 2026
05:58
Retinal Detachment Model in Rodents by Subretinal Injection of Sodium Hyaluronate
Published on: September 11, 2013
[Stickler syndrome with rhegmatogenous retinal detachment]
Hiroka Watanabe1, Kenichi Kohzaki, Hiroyuki Kubo
1Department of Ophthalmology, The Jikei University Hospital, Tokyo, Japan. h-iwata@jikei.ac.jp
Nippon Ganka Gakkai Zasshi
|June 16, 2010
Summary
Pediatric rhegmatogenous retinal detachment can signal Stickler syndrome, an inherited connective tissue disorder. Early diagnosis requires thorough eye exams and family history assessment for affected children.
Area of Science:
- Ophthalmology
- Genetics
- Connective Tissue Diseases
Background:
- Stickler syndrome is an autosomal dominant genetic disorder affecting collagen.
- It causes widespread connective tissue and ocular abnormalities.
Observation:
- A 10-year-old boy presented with rhegmatogenous retinal detachment in his right eye.
- He exhibited high myopia, vitreous liquefaction, lattice degeneration, cleft palate, and a broad nasal bridge.
- Family history revealed eye disease and cleft palate.
Findings:
- The patient was diagnosed with Stickler syndrome.
- Surgical repair included vitrectomy, scleral buckling, encircling, and silicone oil injection for retinal reattachment.
Implications:
- Pediatric retinal detachment warrants consideration of Stickler syndrome.
- Comprehensive ophthalmologic evaluation and detailed family history are crucial for diagnosis.
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