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Updated: Dec 18, 2025

Isolation and Functional Assessment of Human Breast Cancer Stem Cells from Cell and Tissue Samples
Published on: October 2, 2020
Targeting the perpetrator: breast cancer stem cell therapeutics
Arindam Pal1, Kelli E Valdez, Martha Z Carletti
1The University of Kansas Medical Center, 3901 Rainbow Blvd, Lied G015, Kansas City, KS, 66160, USA.
None:
The hypothesis that tumors may originate from a rare population of cancer stem cells (CSCs) has gained tremendous popularity in recent years and is supported extensively by several pioneering works. Cancer therapies targeting CSCs have unlimited potential for relapse free survival of cancer patients. As a result, knowledge of biological pathways that govern CSCs is very important and this review is focused on the biology of CSCs with special emphasis on breast CSCs, and recent advances in therapeutic approaches targeting them.
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