Automated single nucleotide polymorphism typing using bead array in capillary tube
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Visual Detection of Multiple Nucleic Acids in a Capillary Array
Published on: November 15, 2017
Yasuo Kagawa1, Mami Hiraoka, Yukiko Miyashita-Hatano
1High Technology Research Center of Kagawa Nutrition University, 3-9-21 Chiyoda, Sakado, Saitama 350-0288, Japan. kagawa@eiyo.ac.jp
Journal of Bioscience and Bioengineering
|June 16, 2010
Abstract:
A low-cost and simple on-site technique for genotyping single nucleotide polymorphisms (SNPs) was developed. The technique is based on allele-specific primer PCR and the recently developed bead arrays in a single tip technique. The performance of the method was verified by genotyping four SNPs that correlate with cardiovascular diseases.
