Related Experiment Video
Updated: Jun 12, 2026
04:23
A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
Published on: April 28, 2019
[Bilateral optic neuritis after dengue viral infection: case report]
Ricardo Evangelista Marrocos de Aragão1, Ieda Maria Alexandre Barreira, Livia Nogueira Costa Lima
1Hospital Universitário Walter Cantídio, Universidade Federal do Ceará, Fortaleza, CE, Brasil.
Arquivos Brasileiros De Oftalmologia
|June 16, 2010
Summary
Dengue fever can cause neurological issues like bilateral optic neuritis. Fortunately, vision often recovers quickly without specific treatment after a dengue infection.
Area of Science:
- Neurology
- Infectious Diseases
- Ophthalmology
Background:
- Dengue fever is a mosquito-borne viral illness prevalent in over 100 countries.
- Clinical dengue presentation varies, ranging from asymptomatic to severe dengue hemorrhagic or shock syndrome.
- While ocular manifestations are documented, neurological involvement in dengue is less frequently reported.
Observation:
- This report details two cases of bilateral optic neuritis following dengue viral infection.
- Both patients experienced rapid visual acuity recovery.
Findings:
- Bilateral optic neuritis is a potential neurological complication of dengue fever.
- Prompt recovery of visual acuity can occur in these cases, even without specific treatment.
Implications:
- Highlights the importance of considering neurological complications in dengue patients.
- Suggests a favorable prognosis for visual recovery in dengue-associated optic neuritis.
- Underscores the need for further research into dengue's neurological impact.
Related Concept Videos
01:25Arboviral Encephalitis
Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
01:19Encephalitis l: Introduction
Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...
01:18Viral Meningitis
Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
01:26Encephalitis ll: Pathophysiology
Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...
01:27Diabetic Retinopathy
DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
01:27Cytomegalovirus Disease
Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...