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The potential for undertaking slow CT using a modern CT scanner.

C D Chinneck¹, M McJury, A R Hounsell

¹Northern Ireland Cancer Centre, Belfast City Hospital, Belfast Health and Social Care Trust, Lisburn Road, Belfast, UK. Candice.Chinneck@belfasttrust.hscni.net

The British Journal of Radiology

|June 17, 2010

Summary

Slow computed tomography (CT) scanning improves the accuracy of defining moving target volumes in lung cancer patients. This technique offers more precise delineation of tumor boundaries, aiding in better treatment planning and management of respiratory motion.

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Area of Science:

Medical Imaging
Radiotherapy Physics
Oncology

Background:

Respiratory motion significantly impacts the accuracy of target volume definition in lung cancer patients.
Precise delineation of moving target volumes is crucial for effective radiotherapy planning.

Purpose of the Study:

To investigate the efficacy of slow computed tomography (CT) in improving the definition of moving target volumes.
To compare the accuracy and reproducibility of slow CT versus standard CT for target volume delineation.

Main Methods:

Acquisition of standard and slow CT scans of an oscillating phantom with defined spheres (A, B, C).
Analysis of image data to determine central coordinates and calculate the ratio of outlined target volume on CT (TV(CT)) to true target volume (TV).
Evaluation of results for different peak-to-trough (PTT) motion amplitudes (1.5 cm and 2.5 cm).

Main Results:

Slow CT yielded higher TV(CT)/TV ratios (mean 0.9) compared to standard CT (mean 0.7-0.8) for both 1.5 cm and 2.5 cm motion.
Central coordinate deviations were significantly smaller with slow CT (within 0.1 cm) versus standard CT (up to 0.7 cm).
Slow CT demonstrated improved accuracy and reproducibility in defining moving target volumes across different motion ranges.

Conclusions:

Slow CT scanning offers a significant benefit for accurately defining moving target volumes in lung cancer patients.
This technique enhances the management of respiratory motion, even with modern CT scanners.
Slow CT improves the precision and reproducibility of target volume delineation in radiotherapy.