Chronic depression and hospital course in adolescents

Survival curves were used to analyze the relationship between chronicity of depression and hospital course in 48 adolescents with unipolar major depression. The 25 adolescents with chronic depression (defined as a continuous course of depressive illness for 1 year or more) did not differ from those with acute depression in age, gender, or socioeconomic status. Despite similar admission and discharge Children's Depression Rating Scale-Revised scores, adolescents with chronic depression had a significantly slower initial rate of improvement. The study suggests that chronicity of depression has predictive validity with regard to acute hospital course in adolescents.