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Published on: July 19, 2024
Surgical lung biopsies in 418 patients with suspected interstitial lung disease in China
1Department of Respiratory Medicine, Drum Tower Hospital, Nanjing University Medical School, Nanjing, China. dpzhang207@yahoo.com.cn
Background:
The present study was aimed to evaluate the role and safety of surgical lung biopsies (SLB) in patients with interstitial lung disease (ILD) in China.
Methods:
A retrospective analysis of 418 patients with ILD undergoing SLB from Chinese literature and the data of our hospital during the past ten years was performed.
Results:
A total of 418 cases underwent SLB, including open lung biopsy (OLB) in 229 cases and video-assisted thoracoscopic lung biopsy (VATLB) in 189 cases. SLB yielded a specific diagnosis for 88.0% cases, and unclassifiable idiopathic interstitial pneumonia diagnosis was seen in 9.1% cases. The total postoperative complication rate was 12.0% and mortality rate was 1.9%. The diagnostic yield, post-operative complication rate, and mortality rate between VATLB and OLB had no significant difference.
Conclusion:
SLB is a very useful and relatively safe procedure for diagnosis of ILD.